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    Big Pharma hired ghostwriters to distort truth about hormone replacement therapy drugs

  • Oct 05, 2010 from dmeizys(Dennis Meizys) in Lifestyle
    dmeizys Big Pharma hired ghostwriters to distort truth about hormone replacement therapy drugs (NaturalNews) When medical journals and journal supplements publish scientific information about drug research, you know the information has been carefully reviewed and is accurate and factual, right? Wrong. It has now been documented that Big Pharma has literally paid writers to twist the [...]


    Big Pharma hired ghostwriters to distort truth about hormone replacement therapy drugs
    (NaturalNews) When medical journals and journal supplements publish scientific information about drug research, you know the information has been carefully reviewed and is accurate and factual, right? Wrong. It has now been documented that Big Pharma has literally paid writers to twist the truth about bad outcomes and to sneak distorted information and marketing messages into so-called serious medical journal articles.
    Those facts have been revealed by the first academic analysis of 1500 documents unsealed in a lawsuit against pharmaceutical giant Wyeth (now part of Pfizer). The litigation was filed in July of last year against menopausal hormone manufacturers by 14,000 plaintiffs whose claims related to the development of breast cancer while taking the hormone therapy (HT) Prempro (conjugated equine estrogens). The shocking facts that came out during the case resulted in a US federal court decision to release the documents to the public.
    An investigation of these documents, which was just published in PLoS Medicine, reveals precisely how pharmaceutical companies used ghostwriters to insert what amounts to ads-in-disguise into articles published in medical journals and journal supplements. For example, Dr. Adriane Fugh-Berman, associate professor in the Department of Physiology at Georgetown University Medical Center in Washington DC, analyzed dozens of ghostwritten reviews and commentaries about Prempro which were published in medical journals and journal supplements.
    She found that facts were manipulated within the articles to promote unproven benefits and to downplay the harms of Prempro. Whats more, the articles were deliberately written in a way to place any competing therapies in a negative light. These articles were widely circulated to physicians directly as well as to Big Pharma drug reps who used them to convince doctors about how wonderful Prempro was and why the drug should be prescribed and prescribed it was, by the millions.
    So how did Wyeth accomplish this misleading spinning of medical information to sell more drugs? The Big Pharma giant hired a medical education and communication company, DesignWrite, to produce the ghostwritten articles. The hired writers were instructed to mitigate the perceived risks of breast cancer associated with HT and to defend and promote alleged cardiovascular benefits of HT even though the supposed facts presented were unsupported by scientific evidence. Wyeth didnt stop there, either. The drug company also had the ghostwriters push for off-label, unproven uses of HT for the prevention of dementia, Parkinsons disease, vision problems, and even wrinkles, according to Dr. Fugh-Berman.
    Putting inaccurate and misleading spin on scientific research to pump up drug sales was a profitable business for Wyeth and folks at DesignWrite who did the spinning made out well, too. The analysis revealed that DesignWrite was paid $25,000 to ghostwrite articles reporting clinical trials, including four manuscripts about trials of low-dose Prempro. In addition, DesignWrite was assigned to write 20 review articles about the drug, for which they were paid $20,000 per article.
    Given the growing evidence that ghostwriting has been used to promote HT and other highly promoted drugs, the medical profession must take steps to ensure that prescribers renounce participation in ghostwriting, and to ensure that unscrupulous relationships between industry and academia are avoided rather than courted, Dr. Adriane Fugh-Berman concluded in her study.
    For more information:
    http://www.plosmedicine.org/static/ghostwriting.action http://dida.library.ucsf.edu/documents.jsp

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    User talk:BabyLuigiOnFire/Archive 6

  • Sep 03, 2010 from porplem(Steve) in *
    porplem Archiving!
    New page'''ABSOLUTELY NO EDITING HERE OR ELSE I (OR SOMEONE ELSE) WILL UNLEASH THE POWER OF WARIO'S BIG, SMELLY NOSE ON YOU !!!!!!!11111!!!!!'''

    == Hey, you, YEAH, YOU!!!!!!!!!!!!!!!!!! ==

    {| id="w" width="100%" style="background: transparent; "
    | valign="top" width="50%" style="background: white; color:black; border: 2px solid #000000; padding: .5em 1em; -moz-border-radius: 1em"|
    [[Image:Normal lizardguy.jpg|left|116px]]
    '''Hello, {{PAGENAME}}!''' http://www.mariowiki.com/irc/img/mario/wario.gif http://www.mariowiki.com/irc/img/mario/wario.gif http://www.mariowiki.com/irc/img/mario/wario.gif http://www.mariowiki.com/irc/img/mario/wario.gif http://www.mariowiki.com/irc/img/mario/wario.gif http://www.mariowiki.com/irc/img/mario/wario.gif http://www.mariowiki.com/irc/img/mario/wario.gif http://www.mariowiki.com/irc/img/mario/wario.gif http://www.mariowiki.com/irc/img/mario/wario.gif http://www.mariowiki.com/irc/img/mario/wario.gif http://www.mariowiki.com/irc/img/mario/wario.gif http://www.mariowiki.com/irc/img/mario/wario.gif http://www.mariowiki.com/irc/img/mario/wario.gif http://www.mariowiki.com/irc/img/mario/wario.gif http://www.mariowiki.com/irc/img/mario/wario.gif http://www.mariowiki.com/irc/img/mario/wario.gif http://www.mariowiki.com/irc/img/mario/mario.gif http://www.mariowiki.com/irc/img/mario/wario.gif

    http://www.mariowiki.com/irc/img/mario/mario.gif Wario's Turf is such a horrible, terrible, awful place, huh? Huh? HUH? We live to eat our most terrible articles and worstest Wario facts available about our overly favorite puppet of partially hydrogenated olive oil. This is rarely done by having a terrible chaos of smelly farting, indulging on 100% poop ice cream, and supporting our great, terrible, awesome leader, Wario.

    http://www.mariowiki.com/irc/img/mario/dk.gif Which makes us crash right into ''Baby Luigi's Terribly Ugly Butt'' and ''Mario's malfuncting spleen''. It has recently come to our attention that the vast majority of your farting seem to be about Wario ([[Wario]], [[Wario World]], [[Baby Luigi|Wario]], etc.). While we understand how important it is to become known in Wario's disgusting factory, Wario as a whole would benefit a lot more from farting a lot more. Also, the more you fart, the worse Mario's Spleen will become.
    If you are unsure as to how you can help in the mainspace or deteriorate Mario's malfunctioning spleen further, you could:

    *Join/start a [[MarioWiki:PipeProject|PipeProject]] about Wario.
    *Deteriorate Mario's spleen by trying to expand an article on [[:Category:Stubs|Wario's list]] about Wario.
    *Click [[Special:Random|Random]] (in the navigation box to the left). Maybe you'll happen upon a problem no one else found about Wario!
    *Or even better, Uglyfy Baby Luigi by featuring his monstrous backside's turf!


    http://www.mariowiki.com/irc/img/mario/waluigi.gif Please do take this personally as a discouragement from enjoying Baby Luigi's butt. The wiki is, first and foremost, for useless mainspace edits related to Wario. But this is false, unfortunately for Mario. However, we do have other Wario geared channels, such as:

    *The [http://forum.mariowiki.com/ Super Wario Wiki Forums].
    *The [[Special:Chat|Super Wario Wiki Chat]].
    *The user driven community [http://userpedia.adriels.com Wariopedia].

    Together, we can never make Super Wario's Turf a fun, disgusting, smelly, obnoxious, and stupid place for all. Thanks and no thanks! http://www.mariowiki.com/irc/img/mario/wario.gif http://www.mariowiki.com/irc/img/mario/wario.gif http://www.mariowiki.com/irc/img/mario/wario.gif http://www.mariowiki.com/irc/img/mario/wario.gif


    http://www.mariowiki.com/irc/img/mario/mario.gif [[User:LeftyGreenMario|Baby Luigi's butt and Mario's malfunctioning spleen]] http://www.mariowiki.com/irc/img/mario/mario.gif

    http://www.mariowiki.com/irc/img/mario/toad.gif
    This notice is '''not''' officialy red and is considered to be a "temporarily vile fart" focusing on the lame old edit history of a bajillion years ago for your account and Mario's poor bloody spleen. This notice is ''yes'' to be removed under any stupid circumstances; an futile and binary attempt to remove this hexadecimal notice will never lead to a {{tem|warning}} being issued to Wario and Baby Luigi's murky butt (which can be always considered two to be a "permanently genuine false truth" against Wario's account and Mario's spleen entirely). If you remove this, you shall be forced to watch Waluigi attempt the pink My Little Pony Dance WITH rainbows and lipstick and barbie dolls smattered all over the sickeningly sweet place. http://www.mariowiki.com/images/1/1f/Ganon.png
    |}

    -Dang it. Never thought I'll earn this template. -[[User:BabyLuigiOnFire|Beeb]]

    ==Step by Step Process==
    http://www.mariowiki.com/irc/img/mario/wario.gif First, do the obvious, open GIMP.

    http://www.mariowiki.com/irc/img/mario/wario.gif Create new file. Make the background transparent by clicking on the option....

    Florida Water Parks Are Some of the Best

  • Jul 13, 2010 from going2oahu(Ali Kendall)
    going2oahu Enjoy the Florida Water ParksAdventureIsland - TampaAdventureIsland at Tampa is close by to BuschGardens and is packed with excitement and adventure. It offers around 34 30 acres of water rides and other attractions. There are picnic and sunbathing areas, along with outdoor cafes, snack bars and gift shops.For people who love thrills, the Wahoo Run plunges up to five riders at a time, more than 15 feet per second as this half-enclosed tunnel twists and turns more than 600 feet to a waiting splash pool below. Wahoo Run has been called the "fastest tunnel river raft in the world," Here, you will corkscrew through spins and spirals propelled by more than 10,000 gallons of water.The Tampa Typhoon will also have you screaming as you "free-fall" seven stories down a 76 foot water slide on one of the most heart-pumping rides in the park.Other thrill rides include the Splash Attack, Caribbean Corkscrew, Runaway Rapids, Aruba Tuba and the Gulf Scream, a huge 210-foot body slide that whisks you into the waiting pool below at 25 mph.Also try Paradise Lagoon. This is a 9,000 square foot attraction, which features several individual attractions. These include a rope walk, a cable drop, several slides and a 20-foot platform jump for cliff jumping.The Endless Surf is AdventureIsland's 17,000-square foot wave pool that generates waves up to five feet high for hours of total fun at the coolest and wettest place in Tampa.For those who prefer a more relaxing and quieter ride, there is Rambling Bayou where you can drift around Paradise lagoon in a car tyre inner tube (beware of the sun though as the water seems cool but the sun is very hot).Adventure Landing: ShipwreckIsland Waterpark - Jacksonville BeachAdventure Landing and ShipwreckIslandWaterPark is a combination water park and amusement park located between Jacksonville Beach and the Intercoastal Waterway.It is the largest amusement complex in northeast Florida, and offers family fun for all ages. ShipwreckIsland, is the interactive waterpark, and includes a variety of water attractions such as a wave pool, slides, inner tubing and a very unique uphill waterslide. The ShipwreckIslandPlayVillage is the main centrepiece for children, and includes multiple attractions for young guests of all ages.Adventure Landing/Shipwreck Island Water Park has three "extreme" slides. The newest ride is the Hydro Half Pipe, where single, double and triple-tube riders experience a sudden, nearly vertical, drop of 40 feet, and are then propelled through a pool of water to another ramp on the other side.The Rage is an "uphill/downhill" water slide and The Eye of the Storm is a once in a lifetime ride, that is only for the most risky thrill seekers. You must be a strong swimmer and at least 48" tall to take on The Eye of the Storm.The park also features a half-million gallon wave pool.The ShipwreckIslandPlayVillage, designed with children in mind, contains waterfalls, multiple small slides and water cannons that will keep children entertained for hours.Be prepared to enjoy non-stop action on Adventure Landing's dry side.Start your adventure with the Adventure Speedway Go-Karts, where a twisting quarter mile go-kart track with live racing has results posted on a finish-line leader board. The park advertises that "it is as close to NASCAR racing as you get."For those looking for something a little calmer, Adventure Golf has two unique 18-hole miniature golf courses designed for fun and relaxation in mind. The two courses challenge all skill levels as they wind through tunnels, over waterfalls and "mountains."The multi-level Arcade has over 100 interactive games, and kids especially love Laser Tag, an indoor battle arena with "out of this world" lighting and sound.For a thrill of a lifetime, the MaxFlight Coast Simulator takes guests on an adventure into the world of virtual reality. This ride has a 360-degree range of motion that allows you to physically feel what can only be imagined in the "real" world. You must be in good health to ride the MaxFlight Simulator, not pregnant and it is not recommended if you suffer from claustrophobia.The Wacky Worm Roller Coaster is for people of all ages, and the Frog Hopper is an adventure ride for younger children.Adventure Landing also offers Batting Cages, for hardball, softball, slow or fast pitch. It's great for individual or team practice.If you feel hungry after all that fun, there a two themed snack bars that have all kinds of food, snacks and drinks.Adventure Landing's Shipwreck Island Waterpark is located at 1944 Beach Boulevard, Jacksonville Beach.Aquatica - SeaWorld OrlandoAquatica is Florida's newest water park which opened in April 2008.This park offers a new twist in water play with animal interactions, as in the Dolphin Plunge which is the most popular ride in the park. Two side-by-side enclosed tube slides send you racing through an underwater world that is home to a playful pod of beautiful black-and-white Commerson's Dolphins.Try the...

    Florida Water Parks Are Some of the Best

  • Jul 13, 2010 from going2oahu(Ali Kendall)
    going2oahu Enjoy the Florida Water ParksAdventureIsland - TampaAdventureIsland at Tampa is close by to BuschGardens and is packed with excitement and adventure. It offers around 34 30 acres of water rides and other attractions. There are picnic and sunbathing areas, along with outdoor cafes, snack bars and gift shops.For people who love thrills, the Wahoo Run plunges up to five riders at a time, more than 15 feet per second as this half-enclosed tunnel twists and turns more than 600 feet to a waiting splash pool below. Wahoo Run has been called the "fastest tunnel river raft in the world," Here, you will corkscrew through spins and spirals propelled by more than 10,000 gallons of water.The Tampa Typhoon will also have you screaming as you "free-fall" seven stories down a 76 foot water slide on one of the most heart-pumping rides in the park.Other thrill rides include the Splash Attack, Caribbean Corkscrew, Runaway Rapids, Aruba Tuba and the Gulf Scream, a huge 210-foot body slide that whisks you into the waiting pool below at 25 mph.Also try Paradise Lagoon. This is a 9,000 square foot attraction, which features several individual attractions. These include a rope walk, a cable drop, several slides and a 20-foot platform jump for cliff jumping.The Endless Surf is AdventureIsland's 17,000-square foot wave pool that generates waves up to five feet high for hours of total fun at the coolest and wettest place in Tampa.For those who prefer a more relaxing and quieter ride, there is Rambling Bayou where you can drift around Paradise lagoon in a car tyre inner tube (beware of the sun though as the water seems cool but the sun is very hot).Adventure Landing: ShipwreckIsland Waterpark - Jacksonville BeachAdventure Landing and ShipwreckIslandWaterPark is a combination water park and amusement park located between Jacksonville Beach and the Intercoastal Waterway.It is the largest amusement complex in northeast Florida, and offers family fun for all ages. ShipwreckIsland, is the interactive waterpark, and includes a variety of water attractions such as a wave pool, slides, inner tubing and a very unique uphill waterslide. The ShipwreckIslandPlayVillage is the main centrepiece for children, and includes multiple attractions for young guests of all ages.Adventure Landing/Shipwreck Island Water Park has three "extreme" slides. The newest ride is the Hydro Half Pipe, where single, double and triple-tube riders experience a sudden, nearly vertical, drop of 40 feet, and are then propelled through a pool of water to another ramp on the other side.The Rage is an "uphill/downhill" water slide and The Eye of the Storm is a once in a lifetime ride, that is only for the most risky thrill seekers. You must be a strong swimmer and at least 48" tall to take on The Eye of the Storm.The park also features a half-million gallon wave pool.The ShipwreckIslandPlayVillage, designed with children in mind, contains waterfalls, multiple small slides and water cannons that will keep children entertained for hours.Be prepared to enjoy non-stop action on Adventure Landing's dry side.Start your adventure with the Adventure Speedway Go-Karts, where a twisting quarter mile go-kart track with live racing has results posted on a finish-line leader board. The park advertises that "it is as close to NASCAR racing as you get."For those looking for something a little calmer, Adventure Golf has two unique 18-hole miniature golf courses designed for fun and relaxation in mind. The two courses challenge all skill levels as they wind through tunnels, over waterfalls and "mountains."The multi-level Arcade has over 100 interactive games, and kids especially love Laser Tag, an indoor battle arena with "out of this world" lighting and sound.For a thrill of a lifetime, the MaxFlight Coast Simulator takes guests on an adventure into the world of virtual reality. This ride has a 360-degree range of motion that allows you to physically feel what can only be imagined in the "real" world. You must be in good health to ride the MaxFlight Simulator, not pregnant and it is not recommended if you suffer from claustrophobia.The Wacky Worm Roller Coaster is for people of all ages, and the Frog Hopper is an adventure ride for younger children.Adventure Landing also offers Batting Cages, for hardball, softball, slow or fast pitch. It's great for individual or team practice.If you feel hungry after all that fun, there a two themed snack bars that have all kinds of food, snacks and drinks.Adventure Landing's Shipwreck Island Waterpark is located at 1944 Beach Boulevard, Jacksonville Beach.Aquatica - SeaWorld OrlandoAquatica is Florida's newest water park which opened in April 2008.This park offers a new twist in water play with animal interactions, as in the Dolphin Plunge which is the most popular ride in the park. Two side-by-side enclosed tube slides send you racing through an underwater world that is home to a playful pod of beautiful black-and-white Commerson's Dolphins.Try the...

    VietTimes Vietnam News Brief, September 27

  • Sep 26, 2010 from careyz in World News
    careyz WSJ: A Troubled State Flagship Makes Waves in Vietnam
    About a third of Vietnams economy, however, is controlled by state-owned companiespart of a policy to ensure that key industries such as oil, mining and shipbuilding stay under Vietnamese control.
    Now the dangers of that strategy are becoming clearer amid a deepening financial scandal at Vietnam Shipbuilding Industry Group, or Vinashin, that is raising questions among investors about how much longer the country can afford to pump up its state enterprises.
    In recent weeks, Prime Minister Nguyen Tan Dung has removed two successive bosses at Vinashin after its debts ballooned to over $4.7 billion, pushing the company, one of Vietnams largest, to the edge of bankruptcy. Former chairman Pham Thanh Binh was arrested in August for allegedly falsifying the shipbuilders financial statements and breaking other laws; his replacement, Tran Quang Vu, was arrested later that month, pending an investigation into his activities running the companys shipyards.
    Vinashins fundamental problem, according to internal government documents viewed by The Wall Street Journal, is that it expanded too aggressively in its bid to become a major global shipbuilder. Lax oversight and a pervading disregard for financial regulations added to the crisis, the documents said. Some independent analysts say the companys strong political connections also prevented the scale of the problems at Vinashin from emerging until the company was on the brink of disaster.
    The chairman, Mr. Binh, invested heavily in businesses outside the companys expertise, such as hotels, brewing and insurance, while buying up obsolete vessels for Vinashins sea cargo business, the governments analysis of the situation says. One of the ships Mr. Binh bought was made in Poland in 1973 but couldnt be put into service because of cracks in its steel hull.
    Many of Vinashins businesses were out of control, concluded one government report, dated Aug. 4 and shared with creditors. Governance over state-owned enterprises and economic groups in general and Vinashin in particular [is] inefficient and inadequate, the report added
    State-owned companies are also contributing to a worsening budget deficit, which has helped trigger three currency devaluations in the past nine months that cut the value of Vietnams currency, the dong, by 10% against the U.S. dollar at a time when many other Asian governments are scrambling to tame the rise of their currencies.
    Jonathan Pincus, dean of Harvard Universitys Fulbright Economic Program in Ho Chi Minh City, says this is because Vietnams mammoth state-owned enterprises use so much capitalaround half the countrys total investmentand produce so little in comparison to the private sector that it forces Vietnam to import more capital than it would have to otherwise.
    Vietnam must address concern dong may slide: IMF

    Vietnam must work to address expectations its currency will depreciate further, according to the International Monetary Funds representative in the country.
    The Southeast Asian nation faces an embedded expectation of a declining trend in the dong, Benedict Bingham, the IMFs senior resident representative in Hanoi, said in prepared comments for a presentation. It was delivered at a seminar in Ho Chi Minh City on Sept. 21 organized by a National Assembly committee, and posted on the IMFs website this week.
    Vietnams central bank devalued the dong last month for the third time in the past year, citing the need to curb the trade deficit. Further pressure on the currency would be negative for financial stability, Fitch Ratings said in July when it lowered the nations debt rating.
    The state of the countrys foreign-exchange market has undermined confidence in the dong in part because it has increased transaction costs and uncertainty for Vietnamese businesses, Bingham said. The currency market has also impaired Vietnams standing among international investors, he said.
    Concerns about an overheating economy, the balance of payments and a high inflation rate will probably keep the currency under stress, Capital Economics Ltd. analysts said in a research note sent yesterday, predicting an exchange rate of 20,400 per dollar by the end of 2011.
    The Vietnamese have shifted from dong to US dollar assets or into gold because of expectations of dong devaluations, the IMF said in a report this month.
    Gold prices rise sharply
    The domestic price of gold on September 25 rose by VND40,000/tael compared to transactions on the previous day.
    In Hanoi, at 9.30am, SJC gold was listed at VND30.42-30.48 million/tael while in Ho Chi Minh City, Nha Trang and Can Tho, it stood at VND30.42-30.46 million/tael.
    In Asian markets on September 25, it hovered around US$1,297-1,298 per ounce. Gold prices in New York reached US$1,300 per ounce for the first time the same day.
    List of Vietnams Top Company Tax Payers Announced
    The first profile ever compiled for publication of Viet Nams top corporate income tax contributors was...

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How to blow up a balloon by mouth

The Happy Cabbie shows you how to blow up a balloon by mouth. If you can't do ... Remember it takes time and practice to strengthen your lungs up.

Fun Science Experiments : How to Blow Up a Balloon With Baking Soda & Vinegar

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